Well it’s been a rough 3 week long finals week…not sure how that works out but I’m so glad our tests were split up!! So far we’ve had pharmacology, genetics and pathology was today. Medicine is on Monday and then JUST TWO WEEKS until boards. I’m getting secretly terrified, but I’m forcing myself to stay calm and enjoy the last few weeks with my classmates. I’ve been so focused on finals and boards that I haven’t even realized that we’ve had our last lecture together, our last finals week together, our last Tuesday lunchtime scrabble game together (which Nimisha and I won!) and all kinds of other lasts. I’ve been at Purdue for four years now, and I’m excited to start somewhere new, but it’s going to be hard leaving my favorite places behind. There is nowhere else in the world that has a Harry’s Chocolate Shop, Silver Dipper ice cream and Neon Cactus within two blocks of each other. And all those basketball games at Mackey Arena? Priceless. Fountain runs and Wednesday pick-up soccer? Fantastic. Five intramural teams a semester? Best study break ever. But now I get to trade all of that in for seeing patients, learning how to do everything and living in Indy!! Every big change in life has its ups and downs, so I will continue to stay calm and get everything I can out of my last few weeks here =)
Cool things: our classrooms are in Lynn Hall, the veterinary building here on campus, and each year they have a skit night where students make jokes about each other, professors, classes, crazy hours and whatnot, and a few of my classmates made a video to share our point of view from down in the sub-basement. Enjoy!!
The Illegitimate Children of Lynn Hall
In honor of tank-top Fridays, we all sported tanks for our pathology final this morning (even our professor!! who escaped being photographed…)

Tank Top Friday-Suns out, Guns out
- Cool thing I learned this week: seeing as how I relearned 1000 things this week and learned another 1000 things that I didn’t learn the first time, there are so many things I could put here. But one of the most interesting things I learned was all the effects of alcohol on the liver. Sure, we all know it causes fatty liver and then cirrhosis in alcoholics, but do you know why?
1. Metabolism of alcohol leads to a buildup of NADH+ which is used in oxidative phosphorylation to make ATP. This NADH+ is also used to convert DHAP (the useable intermediate in glycolysis (which happens before ox-phos)) to G3P (an unusable for glycolysis intermediate), which is the glycerol backbone for making triglycerides.
2. The more alcohol and sugar you take in, the more DHAP you make, and therefore the more glycerol you make.
3. Acetyl CoA is the end product of alcohol metabolism, and it is the precursor to making fatty acids (which can be added to glycerol to make triglycerides). So you drink more alcohol, you have more substrate.
4. Alcohol activates hormone-sensitive lipase which mobilizes fatty acids from the triglycerides stored in your adipose tissue. So you drink more, you put more fatty acids into your blood which can also go to the liver and accumulate with the other fatty acids.
5. Alcohol inhibits mitochondrial function. Guess what happens in the mitochondria. Beta-oxidation of fatty acids (breakdown for energy). So you drink more, you breakdown less fat and keep it around in your liver.
6. Let’s recap. Alcohol increases glycerol backbone synthesis and fatty acid synthesis = triglyceride formation. Alcohol mobilizes fatty acids from your fat to your liver and prevents their breakdown = some of the fat you already had is now in your liver as well. EQUALS FATTY LIVER WHICH IS NOT GOOD.
So moral of the story, everything in moderation. Because you can bet that on May 22nd after boards, I will be going to Harry’s Chocolate Shop again to have a Colorado Root Beer. Or two. Or three. But definitely not every day, because fatty liver is a very preventable and unfortunate consequence of overindulgence and addiction =( Somewhere I was reading that alcohol complicates up to 20% of hospital admissions in the US. 20%!!!!!!!!!! I definitely understand why it can be a powerful and seemingly harmless addiction at first, but just like obesity and diabetes and meth, uncontrolled alcohol use can complicate so many things in your body.
- Back on a happier note, Spanish phrase of the day: ¿Tiene algún hábito como beber alcohol? = Do you have any habits like drinking alcohol? Wait, guess that wasn’t necessarily happier…
- Tip for success in medical school: Books are WONDERFUL. All kinds of books. Reading books for pleasure is a fantastic break for your mind. But reading books in medical school is great. Our medicine professor has deemed Nimisha, Jeremy and I, “the world’s greatest study group,” and although we certainly don’t deserve that title, we are ALWAYS studying together, which makes life waaaayyyy more enjoyable, and also way more successful. And at any given time we have about six books open. We’ve been watching Doctors in Training (board prep) videos on the big screen at school, and pausing it sometimes to look in the book that came with it, our First Aid, Goljan Pathology, Robbins pathology and the internet when we don’t even know where to look. I know Jeremy learns best in lecture, but even he uses a ton of books. In undergrad, books were useful for a few classes and totally unnecessary for most, but in medical school books are amazing. And the cool thing about Lafayette? Almost every book you would ever need is in your classroom at all hours of the day. So I only have to buy the major books and then study at school to use the rest =)